1998 Apr. Kumamoto Immunochemical Laboratories Inc. established after the reorganization of Kumamoto Immunochemical Laboratories 2000 Apr. Started the gene knockout project Company name changed to TRANS GENIC INC. 2001 Dec. Concluded an agreement of sales for gene sequence of knockout mice with Yamanouchi Pharmaceutical Co., Ltd (Currently:Astellas Pharma Inc). Concluded an agreement of sales for gene sequence of knockout mice with Sumitomo Chemical Co., Ltd. 2002 Dec. Listed on TSE: Mothers 2003 Feb. Concluded an outsourcing agreement for production and preservation of knockout mice with KYOWA HAKKO KOGYO CO., LTD. Jul. Concluded an outsourcing agreement for production and preservation of knockout mice with Shionogi & Co., Ltd. 2004 Feb. Concluded an agreement with Sankyo Co., Ltd. on non-exclusive information disclosure regarding gene functions obtained from knockout mice Mar. Obtained an exclusive right's agreement which enables the use of technology which produces high-affinity antibodies Apr. Launched a new business model for the Knockout Mouse Business with which we license particular Gene Knockout Mice 2005 Jul. Established Kobe Research Center 2006 Feb. Relocated Head Office to Kumamoto City