April 18, 2008

   

Notice of Disclosure of TG Resource Bank® in Public Database


 

We hereby announce that bioresource information listed in TG Resource Bank® , a database of TRANS GENIC INC. (hereinafter referred to as "we"), has been disclosed in "Japan Mouse/Rat Strain Resources Database" (hereinafter referred to as "JMSR").


JMSR is a public database managed by Center for Genetic Resource Information, National Institute of Genetics. It lists information on mice/rats strains owned by research institutes and private companies.

We have cyclopaedically produced a great number of KO mice and ES cells using "exchangeable gene-trap method" and disclose information about them in TG Resource BankR on our website. Based on the information, we license use rights by strain to pharmaceutical companies and research institutes at home and abroad.

It is expected that disclosure of TG Resource BankR in the public database will dramatically increase access to the Bank and raise recognition of it. We will make further efforts to have it more
accessible to more researchers.

The impact this disclosure will have on our business performance is yet unknown, but we intend to make an announcement in the future when it starts to have a significant impact on our business
performance.

　　Reference: Japan Mouse/Rat Strain Resources Database

Name of institution / company
Number of strain listed
TRANS GENIC INC.
2,708
National Institute of Genetics
149
Kumamoto University
894
Kyoto University
384
RIKEN BioResource Center
1,655
Charles River Laboratories Japan, Inc.
32
National Institute of Biomedical Innovation
22
CLEA Japan, Inc.

35

Source: JMSR website (as of April 18, 2008)

Note:

*

Exchangeable Gene-Trap Method

It is a technology to produce genetically engineered mice effectively, invented by Dr. Ken-ichi Yamamura, director of TRANS GENIC INC and professor of Institute of Molecular Embryology and Genetics, Kumamoto University. It completely destroys genes expressed in murine ES cells at random.

Unlike conventional trap methods, it completely destroys genes and the trapped genes are exchangeable with other genes such as human genes and point mutation. Therefore, it is useful for
developing human disease model animals and conducting gene functional analyses precisely.

 
*

TG Resource Bank®

It is a name of our bioresource library on our website.
We have disclosed information of approximately 700 knockout mouse strains and 2,000 knockout ES clones produced by the exchangeable gene-trap method since September 2006.

 


 
 
 
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