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Jul 27, 2009 TRANS GENIC INC. |
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Notice of Conclusion of Joint Research and Development Agreement with International
Medical Center of Japan |
| We hereby announce that TRANS GENIC INC. (hereinafter referred to as "we") and International Medical Center of Japan (Shinjuku-ku, Tokyo, Japan, President: Dr. Takaaki Kirino) concluded a joint research and development agreement on July 27, 2009 to aim for establishing a simple and rapid diagnostic method for H1N1 flu. |
| We will create H1N1-specific antibodies and develop a simple and rapid assay system to detect them with International Medical Center of Japan. This is an urgent project for practical application of the assay system to prepare for a possible pandemic of the H1N1 flu. We will make use of “GANP® Mouse Technology”, our fundamental technology for producing high-affinity antibodies, to create the highly-specific antibodies promptly and effectively. |
| The effects of the joint research on our business performance are as yet unknown, but we will make an announcement as soon as it is revealed to have a significant impact on our future performance. |
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| Reference |
| GANP® Mouse Technology |
| It is our unique technology to produce high-affinity and high-specificity antibodies using genetically engineered mice named "GANP® mice". We regard the technology as a fundamental technology in our antibody-related technological platforms and use it to promote various businesses, such as developing our original products and granting its license to pharmaceutical companies and diagnostic reagent manufacturers to gain profits from their licensing fees and product royalties. |
| - What is GANP (Germinal Center Associated Nuclear Protein)? |
| GANP is a gene discovered by Dr. Nobuo Sakaguchi of Kumamoto University. GANP is expressed in B-cells which produce antibodies and also induces mutation in antibody genes. Therefore it is possible to produce highly-specific antibodies. |
| - What is a GANP® mouse? |
| It is a mouse transfected with GANP gene. |
Sakaguchi N. et al., J Immunol. 2005 Apr 15; 174(8):4485-94. |
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