Press Release-TRANS GENIC INC.

April 20, 2010

TRANS GENIC INC.

Assay System for Cancer Diagnosis Using Urine Samples has been Patented in the U.S.

We hereby announce that TRANS GENIC INC. (headquartered in Kumamoto, Japan, CEO: Ken-ichi Yamamura, hereinafter referred to as “we”) obtained a patent in the U.S. on a highly sensitive immunological assay system for cancer diagnosis using urine samples (Patent No. US7,700,741).

The patent granted this time covers a newly-developed, high-affinity monoclonal antibody against diacetylspermine and a highly-sensitive, simple and noninvasive assay system for cancer diagnosis. Having noticed diacetylspermine secreted in urine is closely linked to carcinogenesis, we developed the antibody to establish the assay system using urine samples. The assay system has already been patented in Japan.

Regarding business related to the assay system, we have been continuously preparing for market launch of extracorporeal diagnostic reagents, based on “a license agreement for cancer diagnosis using urine samples” concluded with a diagnostic reagent manufacturer on July 8, 2008.


Since the patent has already been obtained in the U.S., the assay system developed by us will be protected as an intellectual property right not only in Japan but in the U.S., and therefore it is expected that our business will be strongly supported by the patent.


The potential influence of the patent acquisition on our performance for the fiscal term ending March 2011 is immaterial, and accordingly our consolidated business forecasts remain unchanged.


Reference	：Diacetylspermine
	Diacetylspermine is a kind of substances generically called polyamines existed in the human body. It has been suggested that urinary excretion of polyamines is associated with carcinogenesis. Diacetylspermine, in particular, has recently been shown to be closely linked to carcinogenesis compared to the other polyamines.
	：Noninvasive
	Unlike diagnoses based on the drawing of blood etc., noninvasive diagnostic methods based on man's natural physiological phenomena such as urine enables us to diagnose without considering any unwanted extracorporeal impact that could affect diagnostic results.