Antibody Products

Product NameUrinary Diacetylspermine ELISA Kit

Cat. No.:
KK073
sample

Volume: 80 samples (96 well plate)
Price: inquiry
Data Sheet Data Sheet
Antigen:
GenBank ID:
Immunizing animal:
Purification:
Antibody subclass:
Application ELISA(-μg/mL)
Cross React Human
Others Polyamines are generally believed to function both in protein synthesis and DNA synthesis leading to control cell proliferation. In 1971, Russel firstly reported that total amount of urinary polyamines elevated in cancer patients. And quantitative kit of urinary polyamines were already developed and utilized as a general biochemical examination.
Recently two diacetyl-derivatives, N1, N12-diacetylspermine and N1, N8-diacetylspermidine, were found to be excreted in urine and form 0.6% and 1.4% of total polyamines respectively.
Comparing urine of diseased person with urine of healthy person, some reports suggested the possibility that diacetyl-derivatives correlate to the status of disease more closely than total amount of polyamines.
Our kit is convenient to quantify amount of urinary diacetylspermine by using ELISA method. This kit is only for research use, not for diagnosis.

・Highly sensitive and specific
・Strip type well, antigen pre-coated microplate
・Assay range: 6.25~200nM

Reference
  • Dig Liver Dis. 2005 Mar;37(3):190-4.
    Urine diacetylspermine as a novel tumour maker for pancreatobiliary carcinomas.
    Yamaguchi K, Nakamura M, Shirahane K, Konomi H, Torata N, Hamasaki N, Kawakita M, Tanaka M.
  • Clin Chim Acta. 2010 Dec 14;411(23-24):1894-9.
    Evaluating the utility of N1,N12-diacetylspermine and N1,N8-diacetylspermidine in urine as tumor markers for breast and colorectal cancers.
    Umemori Y, Ohe Y, Kuribayashi K, Tsuji N, Nishidate T, Kameshima H, Hirata K, Watanabe N.
Collaborators

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How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133