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Contract service for non-clinical study

TRANS GENIC offers drug efficiency and pharmacological test, safety pharmacological study, and disposition study using small or large animals at Kobe laboratory and JOINN laboratory in China. TRANS GENIC proposes proper test plan in response to request from customers, and provides high-quality study based on its extensive experience.

Pharmacokinetic Study

TRANS GENIC conducts ADME study with small animals such as mice and large animals such as monkeys using unlabeled substance. ADME studies using various disease-model animals based on its experience in pharmacological test business are also available.
TRANS GENIC provides consulting service on test system construction in response to request from customers based on its extensive experience. Please feel free to contact us.

ADME study with various animals using unlabeled substance

Type of study and method Corresponding Animals
Learning・memory Absorption/Distribution/Metabolism/Excretion study with single administration Monkey
Dog
Rat
Mouse
Absorption/Distribution/Metabolism/Excretion study with multiple administration
Absorption/Distribution/Metabolism/Excretion study with continuous administration (infusion)
StrokeAnalgesia Portal blood sampling, bile sampling[unrestrained] Monkey
Dog
Cerebrospinal fluid (CSF) sampling[unrestrained]
Intracerebral migration study by using microdialysis Monkey

*Other studies are also available. Please contact us.

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ADME study with various disease-model animals using unlabeled substance

Type of study and method Corresponding Animals
ADME study Absorption/Distribution/Metabolism/Excretion study with liver transplant model Monkey
Dog
Rat
Mouse
Absorption/Distribution/Metabolism/Excretion study with hepatic portal-vena cava anastomosed model
Absorption/Distribution/Metabolism/Excretion study with tumor-bearing model
Absorption/Distribution/Metabolism/Excretion study with renal failure model
Absorption/Distribution/Metabolism/Excretion study with hepatic failure model
Absorption/Distribution/Metabolism/Excretion study with cardiac failure model
Hepatic injury Evaluation of absorbency by digestive tract perfusion or digestive tract loop
(blood sampling from peripheral/portal/hepatic vein)

*Other studies are also available. Please contact us.

Consulting service

TRANS GENIC provides consulting service on various pharmacokinetic studies.

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